Field / NGS Labs

NGS Labs Reimagined: Full Digital Control of Genomic Workflows

Next-Generation Sequencing (NGS) labs operate at the forefront of genomics, where accuracy, speed, and traceability are non-negotiable. From library preparation to sequencing runs and downstream analysis, every step must be meticulously orchestrated. Di-LIMS delivers a unified platform to manage this complexity, connecting instruments, standardizing workflows, and offering full visibility across the sequencing lifecycle.

NGS Lab workflow overview

TRUSTED BY

Centre Hospitalier Universitaire Vaudois
Latvia Biomedical Research and Study Center
CERN
Swiss Biobanking Platform
Diesse
Université de Berne
Curio Wellness
ExcellGene

Why NGS Labs Need a Specialized LIMS

Generic LIMS platforms were not designed for the complexity of NGS workflows. Di-LIMS bridges that gap with domain-specific modules built for genomics labs.

Challenge with Traditional LIMSHow Di-LIMS Prevents It
Complex Multi-Step NGS Workflows
Library prep, adapter ligation, sequencing runs, and downstream bioinformatics are disconnected across tools, creating handoff gaps.
End-to-End NGS Workflow Support
Di-LIMS chains every step from sample intake to sequencing result delivery into a single configurable workflow, eliminating data gaps and manual handoffs.
Limited NGS Instrument Traceability
Run metadata from sequencers is manually exported and pasted into spreadsheets, risking version mismatches and loss of run context.
Integrated NGS Instrument Data Capture
Di-LIMS integrates directly with sequencing instruments, capturing run parameters, quality metrics, and outputs automatically with full audit trail.
High-Volume NGS Plate Handling
Managing 96- or 384-well plates across library prep and pooling steps in non-specialized systems is error-prone and slow.
Configurable NGS Plate Workflows
Di-LIMS provides a visual plate editor supporting high-throughput NGS formats with automated well mapping, pooling, and normalization calculations.
Broken Sample Lineage Tracking
Original specimens, extracted DNA/RNA, libraries, and pooled runs lose their connection across steps, making troubleshooting impossible.
End-to-End Sample Lineage Tracking
Every derivative — from primary sample to final library — is automatically linked in Di-LIMS, preserving full genealogy and enabling traceability across the sequencing lifecycle.
Inconsistent Data Across Teams
Lab scientists, bioinformaticians, and project managers work from different data snapshots, creating misalignment and decision delays.
Centralized Role-Based Data Access
A single source of truth with fine-grained role permissions ensures each team sees the right data at the right time, live and in sync.
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Whether running WGS, RNA-seq, or targeted panels, Di-LIMS is built for sequencing labs.

NGS Lab workflow overview

Key Features for NGS Labs

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Plate View Interface

For managing 96- and 384-well sequencing plates

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Instrument Integration

with Qubit, Nanodrop, sequencers (e.g. Illumina)

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Library Preparation Workflows

With reagent tracking and QC checkpoints

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Custom Workflows

Connect Di-LIMS to hospital information systems, EHRs, and cloud genomics platforms via REST API.

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Genealogy Tracking

From source sample to extracted DNA, libraries, and final runs

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Audit Trails

Audit and Role-Based Validations for each step

What You Can Do with Di-LIMS

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Blazing fast

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Workflows

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Sample management

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Printers

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Excel template

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Data view features

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Storage management

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Print label

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Email notification

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Access rights management

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Strategic Value for NGS Labs

Beyond workflow management, Di-LIMS delivers measurable operational and strategic benefits that help NGS labs scale with confidence.

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Faster Time to Result

Automated data capture and pipeline triggers cut manual turnaround steps, accelerating delivery from days to hours.

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Audit-Ready Compliance

Every action is logged with user ID, timestamp, and context — meeting CAP, ISO, CLIA, and GDPR requirements.

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Scale Without Complexity

From a 2-person research team to a 200-sample-per-day clinical lab, Di-LIMS scales without re-implementation.

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Secure Genomic Data Handling

Role-based access, field-level sensitivity tags, and audit trails protect sensitive patient genomic data.

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Cross-Team Collaboration

Wet lab, dry lab, and clinical teams share a single data layer — no more emailed spreadsheets or version conflicts.

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ROI-Driven Implementation

Rapid onboarding, configurable modules, and no per-seat licensing fees make Di-LIMS a cost-effective long-term investment.

Seamless Integration Across Your Sequencing Ecosystem

Di-LIMS seamlessly supports integration with your existing lab infrastructure and instruments.

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Instrument Connectivity

Native integrations with Illumina, Oxford Nanopore, PacBio and more — data flows in automatically.

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Bioinformatics Pipeline Linkage

Trigger analysis pipelines directly from Di-LIMS and pull results back into the sample record.

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Barcode & Label Printing

Assign barcodes at intake and print labels at any workflow step. Full chain of custody from collection to archive.

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REST API & EHR Integration

Connect Di-LIMS to hospital information systems, EHRs, and cloud genomics platforms via REST API.

Ready to Streamline Your NGS Lab?

From library prep to audit-ready reporting, Di-LIMS gives your sequencing lab the foundation it needs to scale.

Frequently Asked Questions

Optimized for Global Standards & Local Needs

Di-LIMS is aligned with CAP, CLIA, ISO/IEC 17025, and GDPR, ensuring your NGS lab operates within the highest regulatory frameworks worldwide.

NGS Lab ISO-GDPR Standards
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